Advanced Synthetic Methodologies

Explore breakthrough research articles, reaction mechanisms, and innovative strategies in organic synthesis.

Research Articles

The Digital Lab: How Computers Are Revolutionizing the Quest for New Catalysts

Explore how computational methods and AI are transforming asymmetric catalysis, accelerating drug discovery and chemical innovation through digital laboratories.

Abigail Russell
Nov 14, 2025

The Green Chemistry Revolution: Asymmetric Oxygenations with H₂O₂ and O₂

Exploring sustainable asymmetric catalysis using environmentally benign oxidants hydrogen peroxide and oxygen for precise chiral molecule synthesis.

Sofia Henderson
Oct 22, 2025

Crafting Chiral Silicon: The Quest to Build Molecular Handedness from the Ground Up

Explore the groundbreaking catalytic asymmetric dehydrogenative Si-H/X-H coupling reaction that enables precise creation of chiral silicon molecules with applications in pharmaceuticals and materials science.

Genesis Rose
Oct 14, 2025

Alchemist's Playbook: Coinage Metals Transforming Propargylic Alcohols into Molecular Treasures

Explore how copper, silver, and gold catalyze remarkable transformations of propargylic alcohols into valuable pharmaceuticals and materials.

Robert West
Aug 09, 2025

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