Advanced Synthetic Methodologies

Explore breakthrough research articles, reaction mechanisms, and innovative strategies in organic synthesis.

Research Articles

Catalyst in a Box: Zeolite-Supported Enantioselective Catalysis

Exploring the revolutionary potential of chiral zeolites in enantioselective catalysis for pharmaceutical and industrial applications.

Joseph James
Oct 29, 2025

The Asymmetric Frontier: Crafting Molecules with Handedness Using Catalytic Alkylation

Explore how catalytic enantioselective alkylation enables precise synthesis of chiral molecules with applications in pharmaceuticals and materials science.

Carter Jenkins
Oct 22, 2025

Molecular Origami: Twisting Molecules with Rhodium to Forge New Medicines

Discover how rhodium-catalyzed enantioselective C–H functionalization revolutionizes asymmetric synthesis for pharmaceutical development

Gabriel Morgan
Oct 08, 2025

The Silent Symphony of Asymmetric Catalysis: How Silyloxyallenes are Composing Chemistry's New Frontier

Explore the groundbreaking field of catalytic enantioselective α-acylvinyl anion reactions using silyloxyallenes, a revolutionary approach in asymmetric synthesis.

Joseph James
Oct 08, 2025

Molecular Origami: Unfolding Rings to Forge New Medicines

Discover how chemists use metal catalysts to perform precise molecular surgery, building complex 3D structures for new medicines through enantioselective ring-opening reactions.

Allison Howard
Aug 23, 2025

The Molecular Handshake: Crafting Life's Asymmetry with Precision

Explore the fascinating world of catalytic enantioselective aldol-type reactions, a precise chemical process that creates mirror-image molecules essential for pharmaceuticals and life sciences.

Adrian Campbell
Aug 23, 2025

The Three-Carbon Ring: How Molecular Origami Builds Life-Saving Medicines

Exploring the science behind catalytic enantioselective cyclopropanation and its role in pharmaceutical development.

Owen Rogers
Aug 22, 2025

Metal Magic: How Asymmetric Catalysts Craft Molecules with Perfect Handedness

Exploring how heterogeneous enantioselective metal catalysis enables precise synthesis of chiral molecules for pharmaceuticals and sustainable chemistry.

Christopher Bailey
Aug 12, 2025

The Alkyne Alchemist: How Copper Unlocks Precision-Built Molecules

Discover how copper hydride catalysis revolutionizes molecular construction through elegant cascade reactions creating enantioenriched 1,1-disubstituted products.

Sofia Henderson
Aug 10, 2025

Illuminating Asymmetry: When Light Meets Metal to Craft Mirror-Image Molecules

A review of enantioselective dual transition metal/photoredox catalysis in drug discovery and materials science

Ava Morgan
Aug 08, 2025

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