Explore the Frontiers of Molecular Construction

Photobiocatalysis merges the selectivity of enzymes with the unique reactivity unlocked by light, offering a sustainable pathway for synthesizing high...

This article addresses the critical scalability challenges hindering the transition of biomimetic catalysts from academic research to industrial-scale...

This article provides a comprehensive comparison between traditional drug discovery methods and modern high-throughput optimization techniques, tailor...

Accurately calculating reaction energy barriers is crucial for modeling biochemical reactions and drug mechanisms, but the computational cost of high-...

This article provides a comprehensive guide to assay-specific spatial bias in high-throughput screening (HTS), a critical issue affecting data quality...

This article provides a comprehensive, intent-driven guide for researchers and drug development professionals struggling with low hit confirmation rat...

Photoenzymatic catalysis is an emerging frontier that merges the precision of biocatalysis with the energy of light to drive novel, sustainable chemic...

Spatial bias is a pervasive and critical challenge in high-throughput screening (HTS) that can significantly increase false positive and false negativ...

This article provides researchers, scientists, and drug development professionals with a comprehensive analysis of the PMP (plate-specific, multiplica...

This article explores the transformative role of foundation models in accelerating the discovery of organic materials for applications ranging from or...

This article provides a comprehensive analysis of light distribution challenges in photoredox catalysis, a critical bottleneck for reproducibility and...

This article addresses the central challenge of oxygen sensitivity in photobiocatalytic reactions, which manifests as both an inhibitory quencher of r...