Advanced Synthetic Methodologies

Explore breakthrough research articles, reaction mechanisms, and innovative strategies in organic synthesis.

Research Articles

Molecular Dumbbells That Switch On Demand: The Rise of High-Yield [3]Rotaxanes

Explore the breakthrough in molecular machines with high-yield [3]rotaxanes that demonstrate reversible acid-base switching behavior for advanced applications in materials science and molecular electronics.

Claire Phillips
Oct 19, 2025

The Art of Molecular Assembly: Building Tiny Machines with Click Chemistry

Explore how click chemistry revolutionized the synthesis of donor-acceptor rotaxanes, enabling efficient construction of molecular machines and nanotechnology applications.

Ellie Ward
Oct 09, 2025

The Invisible Machines: How Rotaxanes and Catenanes Are Weaving the Future of Materials

Exploring the revolutionary potential of mechanically interlocked materials (MIMs) like rotaxanes and catenanes in medicine, nanotechnology, and smart materials.

Easton Henderson
Aug 09, 2025

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