Research Articles
Breaking Aromaticity: The Simple Catalyst Remaking Molecular World
Discover how aminocatalysis is revolutionizing asymmetric synthesis by breaking aromaticity to create complex three-dimensional molecular architectures.
Bicyclic Guanidine Catalysis: Crafting Molecular Asymmetry for Pharmaceutical Innovation
Explore how bicyclic guanidine catalysts enable asymmetric Michael addition reactions to create chiral oxindoles with pharmaceutical applications.
The Art of Molecular Handshakes: Asymmetric 1,3-Dipolar Cycloadditions of Acrylamides
Explore the elegant world of asymmetric 1,3-dipolar cycloadditions of acrylamides - powerful synthetic tools for creating chiral nitrogen-containing heterocycles with applications in drug development and material science.
The Secret Handshakes of Molecules: Chirality, Sulfur, and Phosphorus
Explore the fascinating world of molecular chirality in organophosphorus and organosulfur compounds, and discover how asymmetric synthesis creates life-saving drugs.
The Chiral Chemist's Dream: Taming the Feisty Grignard Reagent
Explore how chemists tamed Grignard reagents for catalytic asymmetric conjugate addition and allylic alkylation, enabling precise synthesis of chiral molecules for pharmaceuticals.
The Renaissance of Chemistry: Thioureas and the Asymmetric Organocatalysis Revolution
Explore how thioureas are revolutionizing asymmetric organocatalysis, enabling greener synthesis of chiral molecules with unprecedented precision.
The Handshake That Changed Chemistry: Crafting Mirror-Image Molecules
Discover how a chiral 1,2-diamine catalyst is revolutionizing asymmetric acylation of alcohols for pharmaceutical and materials science applications.
The Invisible Hand: How Chiral Phase-Transfer Catalysts Craft Mirror-Image Molecules
Comprehensive review of chiral phase-transfer catalysis evolution, mechanisms, and innovative applications in asymmetric synthesis.
Molecular Lego Pieces: How "Sticky" Ionic Liquids Revolutionize Drug Creation
Explore how immobilized chiral ionic liquids enable asymmetric Aza-Michael reactions for sustainable pharmaceutical synthesis.
The Alchemist of Asymmetry: Saturo Masamune's Molecular Mastery
Explore Saturo Masamune's revolutionary work on natural products and strained ring systems that transformed organic synthesis and drug development.