Research Articles
Engineering Biology's Assembly Lines: The Quest to Create Fluorinated Medicines
Discover how scientists are rewiring bacterial biosynthesis pathways to incorporate fluorine into complex natural products, potentially enabling more efficient production of fluorinated drugs.
Nature's Blueprint: How Simple Molecules Are Forging New Medicines
Exploring how phenoxy acetamide derivatives are revolutionizing drug discovery for cancer, neurodegenerative diseases, and antimicrobial resistance.
Molecular Guardians: How the 1-Pyrindane Ring Could Revolutionize Neurodegenerative Disease Treatment
Exploring the potential of 1-pyrindane ring molecules as novel therapeutic agents for treating neurodegenerative diseases like Alzheimer's and Parkinson's.
The Universal Language of Separation: How Chromatography Revolutionizes Drug Discovery
Explore how chromatography has become the universal language in pharmaceutical research, enabling precise drug discovery and development through advanced separation techniques.
From Sand to Surgery: The Sulfonamide-to-Sulfonyl Fluoride Transformation
Discover how the simple chemical transformation of sulfonamides to sulfonyl fluorides is revolutionizing drug discovery and modern chemistry.
The Art of Building Phenanthridinones: Modern Chemistry's Drug Discovery Quest
Explore the synthetic strategies and therapeutic potential of phenanthridinones in modern medicinal chemistry and drug discovery.
The Robot Chemists: Automating the Art of Molecule Building
Explore how automated synthesis is revolutionizing chemistry, accelerating drug discovery and material science through robotic systems and AI.
Molecular Surgery: The Art of Editing Nature's Most Reluctant Bonds
Discover how selective sp3 C–H alkylation via polarity-match-based cross-coupling is revolutionizing drug discovery and molecular design.
The Silent Revolution in Drug Discovery: Activating C-H Bonds
Explore how C-H bond functionalization is transforming pharmaceutical development through targeted molecular modifications of tetrahydropyridopyrimidines and other heterocycles.
Copper Nanoparticles Revolutionize Click Chemistry for Drug Discovery
Discover how copper nanoparticles are transforming click chemistry, enabling precise molecular construction for drug discovery and materials science.